We enrolled 293 patients, 162 of whom were in the 6-month end-point cohort and 151 of whom completed the 6-month follow-up period. The mean age of the patients was 60 years, 16.7% were women, and ...

Adjustment for race is discouraged in lung-function testing, but the implications of adopting race-neutral equations have not been comprehensively quantified. We obtained longitudinal data from ...

Dupilumab, a fully human monoclonal antibody that blocks the shared receptor component for interleukin-4 and interleukin-13, key and central drivers of type 2 inflammation, has shown efficacy and ...

Treatment of acute stroke, before a distinction can be made between ischemic and hemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes ...

At this prespecified interim analysis (median follow-up, 25.4 months), the percentage of patients with 18-month event-free survival was 70.2% in the nivolumab group and 50.0% in the chemotherapy ...

Many persons with chronic obstructive pulmonary disease (COPD) or asthma have not received a diagnosis, so their respiratory symptoms remain largely untreated. We used a case-finding method to ...

In this audio interview conducted on May 14, 2024, the editors are joined by Jeanne Marrazzo, director of the National ...

Dr. Tristan L. Lim (Medicine): A 73-year-old woman was transferred to this hospital because of worsening rash. The patient had been in her usual state of health until 8 days before the current ...

Duration and frequency data are based on an analysis of 50 metropolitan areas in the United States. Years included in the 2020s are 2020 and 2021. Data are from the Environmental Protection Agency.

We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage to receive andexanet or usual care. The primary ...

Including carbon footprint as an end point in randomized, controlled trials could help clinicians, regulators, and policymakers understand the environmental effects of medical interventions.

One of the major determinants of exercise intolerance and limiting symptoms among patients with obstructive hypertrophic cardiomyopathy (HCM) is an elevated intracardiac pressure resulting from ...